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MDM2/XIAP Inhibitor

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100892
    MX69
    1 Publications Verification

    		 MDM-2/p53 IAP E1/E2/E3 Enzyme Cancer
    MX69 is an inhibitor of MDM2/XIAP, used for cancer treatment.
    MX69
  • HY-155571
    MDM2/XIAP-IN-3

    		MDM-2/p53 IAP Cancer
    MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death .
    MDM2/XIAP-IN-3
  • HY-153200
    MDM2/XIAP-IN-2

    		MDM-2/p53 Cancer
    MDM2/XIAP-IN-2 is a dual inhibitor of murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP). MDM2/XIAP-IN-2 degrades MDM2, and inhibits XIAP mRNA translation to inhibits cancer cells. Particularly, MDM2/XIAP-IN-2 inhibits acute lymphoblastic leukemia cell line EU-1 with an IC50 value of 0.3 μM .
    MDM2/XIAP-IN-2
  • HY-153199
    MDM2/XIAP-IN-1

    		Others Cancer
    MDM2/XIAP-IN-1 (compound 14) is an orally active inhibitor of dual MDM2/XIAP. MDM2/XIAP-IN-1 has anti-cancer activity with an IC50 value of 0.3 μM, which can be used in cance rescrch .
    MDM2/XIAP-IN-1

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